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How antibodies are optimized into Optibodies™

BioSiteHisto optimize and fine-tune antibodies for the needs of the clinical IHC laboratory. Only antibodies that fulfill the criterias of optimal staining pattern are incorporated in our premium product portfolio - Optibodies™

Optibodiesis a set of carefully optimized and fine-tuned diagnostically important monoclonal antibodies . The collection is a creation of BioSiteHisto’s immunohistochemistry experts. They are tested and optimized using NordiQC recommendations of control tissues and staining criteria.  Only antibodies that reach excellent results in testing protocol and appropriate control tissues are approved as a part of the collection.

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Synaptophysin [BS15] – Neuroendocrine tumor

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Synaptophysin [BS15] – Appendix stroma

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Synaptophysin [BS15] – Appendix muscular layers

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SOX10 [BS7] – Skin

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SOX10 [BS7] – Melanoma

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SOX10 [BS7] – Breast hyperplasia

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SMA [BS66] – Liver

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SMA [BS66] – Leiomyoma

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SMA [BS66] – Leiomyoma x200

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SMA [BS66] – Leiomyoma x100

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SMA [BS66] – GIST

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Napsin A [BS10] – Lung adenocarcinoma

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Napsin A [BS10] – Lung

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Melan A [BS52] – Skin

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Melan A [BS52] – Melanoma

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Ki67 [BS4] – Tonsil

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Ki67 [BS4] – Ductal breast carcinoma

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Ki67 [BS4] – Appendix

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EPCAM [BS14] – Renal clear cell carcinoma

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EPCAM [BS14] – Kidney

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EPCAM [BS14] – Colon carcinoma

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EPCAM [BS14] – Basal cell carcinoma

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EPCAM [BS14] – Appendix

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E-cadherin [BS38] – Lobular breast carcinoma

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Desmin [BS21] – Rhabdomyosarcoma

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E-cadherin [BS38] – Appendix

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Desmin [BS21] – Appendix

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Desmin [BS21] – Appendix x200

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CKpan [BS5] -Renal clear cell carcinoma

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CKpan [BS5] -Ductal breast carcinoma

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CKpan [BS5] – Xenograft, human carcinoma cells in mouse tissue

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CKpan [BS5] – Appendix

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CK19 [BS23] – Ductal breast carcinoma

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CK19 [BS23] – Appendix

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CEA [BS33] – Colon cancer metastase

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CD38 [BS3] – Appendix

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CD31 [BS50] – Tonsil germinal center

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CD20 [BS6] – Appendix

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CD20 [BS6] – Appendix

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AMACR [BS2] -Prostate (PIN)

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AMACR [BS2] -Kidney

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Frequently asked questions
What address do I use for sending my samples to BioSite Histo?

BioSiteHisto Hermiankatu 3 FI-33720, Tampere Finland T: +358 20 7432 000

How we can send our samples?

Samples can be sent in various forms:

  • Formalin fixed samples
  • Fresh frozen samples
  • Samples in the buffer
  • Paraffin blocks

Can we perform pilot study or stainings?

We are very keen to perform pilot studies and setting up new methods for customer needs. Pilot studies are always welcome. This minimizes risk for both parties.

I have bone samples, is it better to use undecalcified method or decalcified method

This depends on the aims of the study and the tissue size. We in BSH offer three different options to proceed. It is also possible to splice the tissue for two ore more parts and using two or more methods to process. It is identical if immunohistochemistry or other special stainings needed.

      • Decalcifying with EDTA and paraffin embedding. This ensures excellent staining quality and immunohistochemical analysis.
      • Plastic embedding and hard tissue microtoming. Good option for the medical device studies eg. implant studies etc.
      • Plastic embeddien and grinding, for titanium implants and very hard materials.

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